Methixene hydrochloride

Methixene hydrochloride Brand names, Methixene hydrochloride Analogs

Methixene hydrochloride Brand Names Mixture

No information avaliable

Methixene hydrochloride Chemical_Formula

C₁₆H₁₆ClN₃O₃S

Methixene hydrochloride RX_link

http://www.rxlist.com/cgi/generic2/metolazone.htm

Methixene hydrochloride fda sheet

Methixene_hydrochloride FDA

Methixene hydrochloride msds (material safety sheet)

Methixene hydrochloride Synthesis Reference

No information avaliable

Methixene hydrochloride Molecular Weight

365.835 g/mol

Methixene hydrochloride Melting Point

256 ^oC

Methixene hydrochloride H₂O Solubility

60.3 mg/L

Methixene hydrochloride State

Solid

Methixene hydrochloride LogP

2.784

Methixene hydrochloride Dosage Forms

Tablet for oral administration (0.5mg)

Methixene hydrochloride Indication

For the treatment of hypertension, alone or in combination with other antihypertensive drugs of a different class.

Methixene hydrochloride Pharmacology

Metolazone is a quinazoline diuretic, with properties generally similar to the thiazide diuretics. A proximal action of metolazone has been shown in humans by increased excretion of phosphate and magnesium ions and by a markedly increased fractional excretion of sodium in patients with severely compromised glomerular filtration. This action has been demonstrated in animals by micropuncture studies.

Methixene hydrochloride Absorption

Peak blood levels are obtained within 2 to 4 hours of oral administration.

Methixene hydrochloride side effects and Toxicity

Symptoms of overdose include difficulty breathing, dizziness, dizziness on standing up, drowsiness, fainting, irritation of the stomach and intestines, and lethargy leading to coma.

Methixene hydrochloride Patient Information