Methaxalonum
Category
Methaxalonum Brand names, Methaxalonum Analogs
Methaxalonum Brand Names Mixture
No information avaliable
Methaxalonum Chemical_Formula
C12H15NO3
Methaxalonum RX_link
http://www.rxlist.com/cgi/generic/metax.htm
Methaxalonum fda sheet
Methaxalonum msds (material safety sheet)
Methaxalonum Synthesis Reference
No information avaliable
Methaxalonum Molecular Weight
221.252 g/mol
Methaxalonum Melting Point
122 oC
Methaxalonum H2O Solubility
No information avaliable
Methaxalonum State
Solid
Methaxalonum LogP
1.603
Methaxalonum Dosage Forms
Tablets (400 mg round, pale rose tablet and an 800 mg oval, pink scored tablet)
Methaxalonum Indication
For the treatment of painful musculoskeletal conditions
Methaxalonum Pharmacology
Metaxalone is a skeletal muscle relaxant indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomforts associated with acute, painful musculoskeletal conditions. The mode of action of this drug has not been clearly identified, but may be related to its sedative properties. Metaxalone does not directly relax tense skeletal muscles in man.
Methaxalonum Absorption
The absolute bioavailability of metaxalone from Skelaxin tablets is not known.
Methaxalonum Toxicity
LD50=775mg/kg (Rat, oral); LD50=1690 mg/kg (Mouse, oral). When determining the LD50 in rats and mice, progressive sedation, hypnosis and finally respiratoryfailure were noted as the dosage increased. In dogs, no LD50 could be determined as the higher doses produced an emetic action in 15 to 30 minutes.
Methaxalonum Patient Information
Patient Information:
Use Metaxalone with caution. It may affect driving, operating machinery or other hazarous activities. Metaxalone may increase the effects of alcohol
and other central nervous system depressants.
If you have liver problems or you are breast feeding, discuss with your doctor about the risks of taking the Metaxalone.
Methaxalonum Organisms Affected
Humans and other mammals
