Metaxalona_[Inn-Spanish]

Category

Metaxalona_[Inn-Spanish]




Useful info

Metaxalona_[Inn-Spanish] Brand names, Metaxalona_[Inn-Spanish] Analogs

Metaxalona_[Inn-Spanish] Brand Names Mixture

  • No information avaliable

    • Metaxalona_[Inn-Spanish] Chemical_Formula

    C12H15NO3

    Metaxalona_[Inn-Spanish] RX_link

    http://www.rxlist.com/cgi/generic/metax.htm

    Metaxalona_[Inn-Spanish] fda sheet

    Metaxalona_[Inn-Spanish] FDA

    Metaxalona_[Inn-Spanish] msds (material safety sheet)

    Metaxalona_[Inn-Spanish] Synthesis Reference

    No information avaliable

    Metaxalona_[Inn-Spanish] Molecular Weight

    221.252 g/mol

    Metaxalona_[Inn-Spanish] Melting Point

    122 oC

    Metaxalona_[Inn-Spanish] H2O Solubility

    No information avaliable

    Metaxalona_[Inn-Spanish] State

    Solid

    Metaxalona_[Inn-Spanish] LogP

    1.603

    Metaxalona_[Inn-Spanish] Dosage Forms

    Tablets (400 mg round, pale rose tablet and an 800 mg oval, pink scored tablet)

    Metaxalona_[Inn-Spanish] Indication

    For the treatment of painful musculoskeletal conditions

    Metaxalona_[Inn-Spanish] Pharmacology

    Metaxalone is a skeletal muscle relaxant indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomforts associated with acute, painful musculoskeletal conditions. The mode of action of this drug has not been clearly identified, but may be related to its sedative properties. Metaxalone does not directly relax tense skeletal muscles in man.

    Metaxalona_[Inn-Spanish] Absorption

    The absolute bioavailability of metaxalone from Skelaxin tablets is not known.

    Metaxalona_[Inn-Spanish] Toxicity

    LD50=775mg/kg (Rat, oral); LD50=1690 mg/kg (Mouse, oral). When determining the LD50 in rats and mice, progressive sedation, hypnosis and finally respiratoryfailure were noted as the dosage increased. In dogs, no LD50 could be determined as the higher doses produced an emetic action in 15 to 30 minutes.

    Metaxalona_[Inn-Spanish] Patient Information

    Patient Information:

    Use Metaxalone with caution. It may affect driving, operating machinery or other hazarous activities. Metaxalone may increase the effects of alcohol
    and other central nervous system depressants.

    If you have liver problems or you are breast feeding, discuss with your doctor about the risks of taking the Metaxalone.

    Metaxalona_[Inn-Spanish] Organisms Affected

    Humans and other mammals