Metaxalon
Category
Metaxalon Brand names, Metaxalon Analogs
Metaxalon Brand Names Mixture
No information avaliable
Metaxalon Chemical_Formula
C12H15NO3
Metaxalon RX_link
http://www.rxlist.com/cgi/generic/metax.htm
Metaxalon fda sheet
Metaxalon msds (material safety sheet)
Metaxalon Synthesis Reference
No information avaliable
Metaxalon Molecular Weight
221.252 g/mol
Metaxalon Melting Point
122 oC
Metaxalon H2O Solubility
No information avaliable
Metaxalon State
Solid
Metaxalon LogP
1.603
Metaxalon Dosage Forms
Tablets (400 mg round, pale rose tablet and an 800 mg oval, pink scored tablet)
Metaxalon Indication
For the treatment of painful musculoskeletal conditions
Metaxalon Pharmacology
Metaxalone is a skeletal muscle relaxant indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomforts associated with acute, painful musculoskeletal conditions. The mode of action of this drug has not been clearly identified, but may be related to its sedative properties. Metaxalone does not directly relax tense skeletal muscles in man.
Metaxalon Absorption
The absolute bioavailability of metaxalone from Skelaxin tablets is not known.
Metaxalon Toxicity
LD50=775mg/kg (Rat, oral); LD50=1690 mg/kg (Mouse, oral). When determining the LD50 in rats and mice, progressive sedation, hypnosis and finally respiratoryfailure were noted as the dosage increased. In dogs, no LD50 could be determined as the higher doses produced an emetic action in 15 to 30 minutes.
Metaxalon Patient Information
Patient Information:
Use Metaxalone with caution. It may affect driving, operating machinery or other hazarous activities. Metaxalone may increase the effects of alcohol
and other central nervous system depressants.
If you have liver problems or you are breast feeding, discuss with your doctor about the risks of taking the Metaxalone.
Metaxalon Organisms Affected
Humans and other mammals
