Mephyton_(TN)

Category

Mephyton_(TN)




Useful info

Mephyton_(TN) Brand names, Mephyton_(TN) Analogs

Mephyton_(TN) Brand Names Mixture

  • No information avaliable
  • Mephyton_(TN) Chemical_Formula

    C31H46O2

    Mephyton_(TN) RX_link

    http://www.rxlist.com/cgi/generic3/phytonadione.htm

    Mephyton_(TN) fda sheet

    Mephyton_(TN) msds (material safety sheet)

    Mephyton_(TN) Synthesis Reference

    No information avaliable

    Mephyton_(TN) Molecular Weight

    450.696 g/mol

    Mephyton_(TN) Melting Point

    -20 oC

    Mephyton_(TN) H2O Solubility

    Insoluble in water

    Mephyton_(TN) State

    Liquid

    Mephyton_(TN) LogP

    8.841

    Mephyton_(TN) Dosage Forms

    Liquid

    Mephyton_(TN) Indication

    For the treatment of haemorrhagic conditions in infants, antidote for coumarin anticoagulants in hypoprothrombinaemia

    Mephyton_(TN) Pharmacology

    Phytonadione is a vitamin, indicated in the treatment of coagulation disorders which are due to faulty formation of factors II, VII, IX and X when caused by vitamin K deficiency or interference with vitamin K activity. Phytonadione aqueous colloidal solution of vitamin K1 for parenteral injection, possesses the same type and degree of activity as does naturally-occurring vitamin K, which is necessary for the production via the liver of active prothrombin (factor II), proconvertin (factor VII), plasma thromboplastin component (factor IX), and Stuart factor (factor X).

    Mephyton_(TN) Absorption

    Oral phytonadione is adequately absorbed from the gastrointestinal tract only if bile salts are present. After absorption, phytonadione is initially concentrated in the liver, but the concentration declines rapidly. Very little vitamin K accumulates in tissues.

    Mephyton_(TN) Toxicity

    No information avaliable

    Mephyton_(TN) Patient Information

    No information avaliable

    Mephyton_(TN) Organisms Affected

    Humans and other mammals