Mephyton
Category
Mephyton Brand names, Mephyton Analogs
Mephyton Brand Names Mixture
No information avaliable
Mephyton Chemical_Formula
C31H46O2
Mephyton RX_link
http://www.rxlist.com/cgi/generic3/phytonadione.htm
Mephyton fda sheet
Mephyton msds (material safety sheet)
Mephyton Synthesis Reference
No information avaliable
Mephyton Molecular Weight
450.696 g/mol
Mephyton Melting Point
-20 oC
Mephyton H2O Solubility
Insoluble in water
Mephyton State
Liquid
Mephyton LogP
8.841
Mephyton Dosage Forms
Liquid
Mephyton Indication
For the treatment of haemorrhagic conditions in infants, antidote for coumarin anticoagulants in hypoprothrombinaemia
Mephyton Pharmacology
Phytonadione is a vitamin, indicated in the treatment of coagulation disorders which are due to faulty formation of factors II, VII, IX and X when caused by vitamin K deficiency or interference with vitamin K activity. Phytonadione aqueous colloidal solution of vitamin K1 for parenteral injection, possesses the same type and degree of activity as does naturally-occurring vitamin K, which is necessary for the production via the liver of active prothrombin (factor II), proconvertin (factor VII), plasma thromboplastin component (factor IX), and Stuart factor (factor X).
Mephyton Absorption
Oral phytonadione is adequately absorbed from the gastrointestinal tract only if bile salts are present. After absorption, phytonadione is initially concentrated in the liver, but the concentration declines rapidly. Very little vitamin K accumulates in tissues.
Mephyton Toxicity
No information avaliable
Mephyton Patient Information
No information avaliable
Mephyton Organisms Affected
Humans and other mammals
