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Medipo Brand names, Medipo Analogs

Medipo Brand Names Mixture

  • No information avaliable

Medipo Chemical_Formula

C25H38O5

Medipo RX_link

http://www.rxlist.com/cgi/generic/simva.htm

Medipo fda sheet

Medipo FDA

Medipo msds (material safety sheet)

Medipo Synthesis Reference

W. F. Hoffman et al., U.S. Pat. 4,444,784 (1984)

Medipo Molecular Weight

418.566 g/mol

Medipo Melting Point

135-138oC

Medipo H2O Solubility

0.76 mg/L

Medipo State

Solid

Medipo LogP

4.937

Medipo Dosage Forms

Tablet (oral)

Medipo Indication

For the treatment of hypercholesterolemia.

Medipo Pharmacology

Simvastatin, the methylated form of lovastatin, is an oral antilipemic agent which inhibits HMG-CoA reductase. simvastatin is used in the treatment of primary hypercholesterolemia and is effective in reducing total and LDL-cholesterol as well as plasma triglycerides and apolipoprotein B.

Medipo Absorption

Absorption of simvastatin, estimated relative to an intravenous reference dose, in each of two animal species tested, averaged about 85% of an oral dose. In animal studies, after oral dosing, simvastatin achieved substantially higher concentrations in the liver than in non-target tissues.

Medipo side effects and Toxicity

No information avaliable

Medipo Patient Information

Patients should be advised about substances they should not take concomitantly with simvastatin and be advised to report promptly unexplained muscle pain, tenderness, or weakness. Patients should also be advised to inform other physicians prescribing a new medication that they are taking ZOCOR.

Medipo Organisms Affected

Humans and other mammals