Masoprocolum_[INN-Latin]

Category

Masoprocolum_[INN-Latin]




Useful info

Masoprocolum_[INN-Latin] Brand names, Masoprocolum_[INN-Latin] Analogs

Masoprocolum_[INN-Latin] Brand Names Mixture

  • No information avaliable

    • Masoprocolum_[INN-Latin] Chemical_Formula

    C22H30O3

    Masoprocolum_[INN-Latin] RX_link

    http://www.rxlist.com/cgi/generic4/megace_es.htm

    Masoprocolum_[INN-Latin] fda sheet

    Masoprocolum_[INN-Latin] FDA

    Masoprocolum_[INN-Latin] msds (material safety sheet)

    Masoprocolum_[INN-Latin] MSDS

    Masoprocolum_[INN-Latin] Synthesis Reference

    No information avaliable

    Masoprocolum_[INN-Latin] Molecular Weight

    342.472 g/mol

    Masoprocolum_[INN-Latin] Melting Point

    218.0-220.0oC

    Masoprocolum_[INN-Latin] H2O Solubility

    2 µg/mL (at 37°C for the acetate salt)

    Masoprocolum_[INN-Latin] State

    Solid

    Masoprocolum_[INN-Latin] LogP

    3.123

    Masoprocolum_[INN-Latin] Dosage Forms

    Oral suspension containing 125 mg of megestrol acetate per mL; Tablet

    Masoprocolum_[INN-Latin] Indication

    For the treatment of anorexia, cachexia, or an unexplained, significant weight loss in patients with a diagnosis of acquired immunodeficiency syndrome (AIDS). Also used to treat breast cancer, endometrial cancer, and prostate cancer in Canada and some other countries.

    Masoprocolum_[INN-Latin] Pharmacology

    Megestrol is a synthetic progestin and has the same physiologic effects as natural progesterone. The precise mechanism of megestrol’s antianorexic and anticachetic effects is unknown. Initially developed as a contraceptive, it was first evaluated in breast cancer treatment in 1967.

    Masoprocolum_[INN-Latin] Absorption

    Variable, but well absorbed orally.

    Masoprocolum_[INN-Latin] Toxicity

    No serious unexpected side effects have resulted from studies involving megestrol acetate oral suspension administered in dosages as high as 1200 mg/day.

    Masoprocolum_[INN-Latin] Patient Information

    No information avaliable

    Masoprocolum_[INN-Latin] Organisms Affected

    Humans and other mammals