Marzine

• Antiemetics
• Piperazine Derivatives
• ATC:R06AE03
• ATC:R06AE04

• Ciclizina
• Ciclizina [Inn-Spanish]
• Cyclizine Chloride
• Cyclizine Hydrochloride
• Cyclizine [Ban:Dcf:Inn]
• Cyclizinum [Inn-Latin]
• Emoquil
• Marazine
• Marezine
• Marezine Hydrochloride
• Marzine
• Nautazine
• Ne-Devomit
• Neo-Devomit
• Reis-Fit
• Valoid
• Wellcome

• No information avaliable

C₁₈H₂₂N₂

No information avaliable

No information avaliable

266.381 g/mol

No information avaliable

No information avaliable

Solid

3.338

Liquid

For prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness, and vertigo (dizziness caused by other medical problems).

Cyclizine is a piperazine-derivative antihistamine used as an antivertigo/antiemetic agent. Cyclizine is used in the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness. Additionally, it has been used in the management of vertigo in diseases affecting the vestibular apparatus. Although the mechanism by which cyclizine exerts its antiemetic and antivertigo effects has not been fully elucidated, its central anticholinergic properties are partially responsible. The drug depresses labyrinth excitability and vestibular stimulation, and it may affect the medullary chemoreceptor trigger zone. It also possesses anticholinergic, antihistaminic, central nervous system depressant, and local anesthetic effects.

No information avaliable

No information avaliable

No information avaliable

Humans and other mammals