M.V.I._Pediatric
Category
M.V.I._Pediatric Brand names, M.V.I._Pediatric Analogs
M.V.I._Pediatric Brand Names Mixture
No information avaliable
M.V.I._Pediatric Chemical_Formula
C31H46O2
M.V.I._Pediatric RX_link
http://www.rxlist.com/cgi/generic3/phytonadione.htm
M.V.I._Pediatric fda sheet
M.V.I._Pediatric msds (material safety sheet)
M.V.I._Pediatric Synthesis Reference
No information avaliable
M.V.I._Pediatric Molecular Weight
450.696 g/mol
M.V.I._Pediatric Melting Point
-20 oC
M.V.I._Pediatric H2O Solubility
Insoluble in water
M.V.I._Pediatric State
Liquid
M.V.I._Pediatric LogP
8.841
M.V.I._Pediatric Dosage Forms
Liquid
M.V.I._Pediatric Indication
For the treatment of haemorrhagic conditions in infants, antidote for coumarin anticoagulants in hypoprothrombinaemia
M.V.I._Pediatric Pharmacology
Phytonadione is a vitamin, indicated in the treatment of coagulation disorders which are due to faulty formation of factors II, VII, IX and X when caused by vitamin K deficiency or interference with vitamin K activity. Phytonadione aqueous colloidal solution of vitamin K1 for parenteral injection, possesses the same type and degree of activity as does naturally-occurring vitamin K, which is necessary for the production via the liver of active prothrombin (factor II), proconvertin (factor VII), plasma thromboplastin component (factor IX), and Stuart factor (factor X).
M.V.I._Pediatric Absorption
Oral phytonadione is adequately absorbed from the gastrointestinal tract only if bile salts are present. After absorption, phytonadione is initially concentrated in the liver, but the concentration declines rapidly. Very little vitamin K accumulates in tissues.
M.V.I._Pediatric Toxicity
No information avaliable
M.V.I._Pediatric Patient Information
No information avaliable
M.V.I._Pediatric Organisms Affected
Humans and other mammals
