M-AMSA
M-AMSA Brand names, M-AMSA Analogs
M-AMSA Brand Names Mixture
- No information avaliable
M-AMSA Chemical_Formula
C21H19N3O3S
M-AMSA RX_link
No information avaliable
M-AMSA fda sheet
M-AMSA msds (material safety sheet)
M-AMSA Synthesis Reference
No information avaliable
M-AMSA Molecular Weight
393.46 g/mol
M-AMSA Melting Point
234-236oC
M-AMSA H2O Solubility
<1 mg/mL
M-AMSA State
Solid
M-AMSA LogP
5.273
M-AMSA Dosage Forms
Liquid
M-AMSA Indication
For treatment of acute myeloid leukaemia.
M-AMSA Pharmacology
Amsacrine is an aminoacridine derivative that is a potent intercalating antineoplastic agent. It is effective in the treatment of acute leukemias and malignant lymphomas, but has poor activity in the treatment of solid tumors. It is frequently used in combination with other antineoplastic agents in chemotherapy protocols. It produces consistent but acceptable myelosuppression and cardiotoxic effects.
M-AMSA Absorption
Poorly absorbed
M-AMSA side effects and Toxicity
Symptoms of overdose include nausea and vomiting, diarrhea, some cardiotoxicity (rarely).
M-AMSA Patient Information
No information avaliable
M-AMSA Organisms Affected
Humans and other mammals
