Lyophilized_Cytoxan

Category

Lyophilized_Cytoxan




Useful info

Lyophilized_Cytoxan Brand names, Lyophilized_Cytoxan Analogs

Lyophilized_Cytoxan Brand Names Mixture

  • Procytox for Injection 2000mg Pws Iv (Cyclophosphamide + Sodium Chloride)

    • Lyophilized_Cytoxan Chemical_Formula

    C7H15Cl2N2O2P

    Lyophilized_Cytoxan RX_link

    http://www.rxlist.com/cgi/generic3/cyclophosphamide.htm

    Lyophilized_Cytoxan fda sheet

    http://www.accessdata.fda.gov/scripts/cder/onctools/labels.cfm?GN=cyclophosphamide

    Lyophilized_Cytoxan msds (material safety sheet)

    Lyophilized_Cytoxan MSDS

    Lyophilized_Cytoxan Synthesis Reference

    Arnold et al, Angew.Chem., 70; 539; 543(1958)

    Lyophilized_Cytoxan Molecular Weight

    261.085 g/mol

    Lyophilized_Cytoxan Melting Point

    41-45 oC

    Lyophilized_Cytoxan H2O Solubility

    Soluble. 1-5 g/100 mL at 23 oC

    Lyophilized_Cytoxan State

    solid

    Lyophilized_Cytoxan LogP

    No information avaliable

    Lyophilized_Cytoxan Dosage Forms

    Oral tablets; Oral liquid; Parenteral solution

    Lyophilized_Cytoxan Indication

    For management of malignant lymphomas, multiple myeloma,leukemias, mycosis fungoides (advanced disease), neuroblastoma (disseminated disease), adenocarcinoma of the ovary, retinoblastoma and carcinoma of the breast

    Lyophilized_Cytoxan Pharmacology

    Cyclophosphamide is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

    Lyophilized_Cytoxan Absorption

    90-100%

    Lyophilized_Cytoxan Toxicity

    infection, myelosuppression, and cardiac toxicity

    Lyophilized_Cytoxan Patient Information

    This medicine is a type of chemotherapy for treating cancers of the blood
    and certain other cancers. This medicine interferes with the way cancer
    cells grow. Take your doses on a regular scheduled time and DO NOT take
    this medicine more often than directed by your health care provider.
    Finish the full course prescribed by your health care provider. DO NOT
    stop taking this medicine unless diredted to do so by your health care
    provider. While taking this medicine, you make get infection more easily.
    Call your doctor if you get a fever, chills, or sore throat. Drink plenty
    of water with this medicine.

    Lyophilized_Cytoxan Organisms Affected

    Humans and other mammals