Lumigan
Lumigan Brand names, Lumigan Analogs
Lumigan Brand Names Mixture
- No information avaliable
Lumigan Chemical_Formula
C25H37NO4
Lumigan RX_link
http://www.rxlist.com/cgi/generic2/bimatoprost.htm
Lumigan fda sheet
Lumigan msds (material safety sheet)
Lumigan Synthesis Reference
No information avaliable
Lumigan Molecular Weight
415.566 g/mol
Lumigan Melting Point
No information avaliable
Lumigan H2O Solubility
Slightly soluble
Lumigan State
Solid
Lumigan LogP
2.436
Lumigan Dosage Forms
Ophthalmic solution (0.03%)
Lumigan Indication
For the reduction of elevated intraocular pressure in patients with open angle glaucoma or ocular hypertension who are intolerant of other intraocular pressure lowering medications or insufficiently responsive (failed to achieve target IOP determined after multiple measurements over time) to another intraocular pressure lowering medication.
Lumigan Pharmacology
Bimatoprost is a prostamide, a synthetic structural analog of prostaglandin with ocular hypotensive activity. It selectively mimics the effects of naturally occurring substances, prostamides. Bimatoprost lowers intraocular pressure (IOP) in humans. Elevated IOP presents a major risk factor for glaucomatous field loss. The higher the level of IOP, the greater the likelihood of optic nerve damage and visual field loss.
Lumigan Absorption
Systemically absorbed when administered to the eye.
Lumigan side effects and Toxicity
In oral (by gavage) mouse and rat studies, doses up to 100 mg/kg/day did not produce any toxicity. This dose expressed as mg/m2 is at least 70 times higher than the accidental dose of one bottle of bimatoprost for a 10 kg child.
Lumigan Patient Information
Lumigan Organisms Affected
Humans and other mammals
