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Loxitane Brand names, Loxitane Analogs

Loxitane Brand Names Mixture

  • No information avaliable

Loxitane Chemical_Formula

C18H18ClN3O

Loxitane RX_link

http://www.rxlist.com/cgi/generic2/loxapineoc.htm

Loxitane fda sheet

Loxitane msds (material safety sheet)

Loxitane Synthesis Reference

Neth. pat. Appl. 6,406,089 corresp to Schmutz et al., U.S. pat. 3,546,226 (1964, 1970 both to Wander)

Loxitane Molecular Weight

327.808 g/mol

Loxitane Melting Point

109-110 oC

Loxitane H2O Solubility

No information avaliable

Loxitane State

Solid

Loxitane LogP

3.162

Loxitane Dosage Forms

Tablet; Capsule; Oral solution; IV solution; IM solution

Loxitane Indication

For the management of the manifestations of psychotic disorders

Loxitane Pharmacology

Loxapine, a dibenzoxazepine compound, represents a subclass of tricyclic antipsychotic agents, chemically distinct from the thioxanthenes, butyrophenones, and phenothiazines. Pharmacologically, Loxapine is a tranquilizer for which the exact mode of action has not been established.

Loxitane Absorption

Systemic bioavailability of the parent drug was only about one third that after an equivalent intramuscular dose (25 mg base) in male volunteers

Loxitane side effects and Toxicity

LD50=65 mg/kg (Orally in mice)

Loxitane Patient Information

Loxitane Organisms Affected

Humans and other mammals