Loxapin
Loxapin Brand names, Loxapin Analogs
Loxapin Brand Names Mixture
- No information avaliable
Loxapin Chemical_Formula
C18H18ClN3O
Loxapin RX_link
http://www.rxlist.com/cgi/generic2/loxapineoc.htm
Loxapin fda sheet
Loxapin msds (material safety sheet)
Loxapin Synthesis Reference
Neth. pat. Appl. 6,406,089 corresp to Schmutz et al., U.S. pat. 3,546,226 (1964, 1970 both to Wander)
Loxapin Molecular Weight
327.808 g/mol
Loxapin Melting Point
109-110 oC
Loxapin H2O Solubility
No information avaliable
Loxapin State
Solid
Loxapin LogP
3.162
Loxapin Dosage Forms
Tablet; Capsule; Oral solution; IV solution; IM solution
Loxapin Indication
For the management of the manifestations of psychotic disorders
Loxapin Pharmacology
Loxapine, a dibenzoxazepine compound, represents a subclass of tricyclic antipsychotic agents, chemically distinct from the thioxanthenes, butyrophenones, and phenothiazines. Pharmacologically, Loxapine is a tranquilizer for which the exact mode of action has not been established.
Loxapin Absorption
Systemic bioavailability of the parent drug was only about one third that after an equivalent intramuscular dose (25 mg base) in male volunteers
Loxapin side effects and Toxicity
LD50=65 mg/kg (Orally in mice)
Loxapin Patient Information
Loxapin Organisms Affected
Humans and other mammals
