Loxapac
Loxapac Brand names, Loxapac Analogs
Loxapac Brand Names Mixture
- No information avaliable
Loxapac Chemical_Formula
C18H18ClN3O
Loxapac RX_link
http://www.rxlist.com/cgi/generic2/loxapineoc.htm
Loxapac fda sheet
Loxapac msds (material safety sheet)
Loxapac Synthesis Reference
Neth. pat. Appl. 6,406,089 corresp to Schmutz et al., U.S. pat. 3,546,226 (1964, 1970 both to Wander)
Loxapac Molecular Weight
327.808 g/mol
Loxapac Melting Point
109-110 oC
Loxapac H2O Solubility
No information avaliable
Loxapac State
Solid
Loxapac LogP
3.162
Loxapac Dosage Forms
Tablet; Capsule; Oral solution; IV solution; IM solution
Loxapac Indication
For the management of the manifestations of psychotic disorders
Loxapac Pharmacology
Loxapine, a dibenzoxazepine compound, represents a subclass of tricyclic antipsychotic agents, chemically distinct from the thioxanthenes, butyrophenones, and phenothiazines. Pharmacologically, Loxapine is a tranquilizer for which the exact mode of action has not been established.
Loxapac Absorption
Systemic bioavailability of the parent drug was only about one third that after an equivalent intramuscular dose (25 mg base) in male volunteers
Loxapac side effects and Toxicity
LD50=65 mg/kg (Orally in mice)
Loxapac Patient Information
Loxapac Organisms Affected
Humans and other mammals
