Lotrimin_Ultra
Category
Lotrimin_Ultra Brand names, Lotrimin_Ultra Analogs
Lotrimin_Ultra Brand Names Mixture
No information avaliable
Lotrimin_Ultra Chemical_Formula
C23H27N
Lotrimin_Ultra RX_link
http://www.rxlist.com/cgi/generic2/butenafine.htm
Lotrimin_Ultra fda sheet
Lotrimin_Ultra msds (material safety sheet)
Lotrimin_Ultra Synthesis Reference
No information avaliable
Lotrimin_Ultra Molecular Weight
317.467 g/mol
Lotrimin_Ultra Melting Point
No information avaliable
Lotrimin_Ultra H2O Solubility
Slightly soluble (HCl salt)
Lotrimin_Ultra State
Solid
Lotrimin_Ultra LogP
7.12
Lotrimin_Ultra Dosage Forms
Cream (10 mg drug per gram of cream)
Lotrimin_Ultra Indication
For the topical treatment of the following dermatologic infections: tinea (pityriasis) versicolor due to M. furfur, interdigital tinea pedis (athlete’s foot), tinea corporis (ringworm) and tinea cruris (jock itch) due to E. floccosum, T. mentagrophytes, T. rubrum, and T. tonsurans.
Lotrimin_Ultra Pharmacology
Butenafine is an antifungal agent that acts by inhibiting squalene epoxidase, thus blocking the biosynthesis of ergosterol, an essential component of fungal cell membranes. It is mainly active against dermatophytes and has superior fungicidal activity against this group of fungi when compared to that of terbinafine, naftifine, tolnaftate, clotrimazole, and bifonazole. It is active also against Candida albicans and this activity is superior to that of terbinafine and naftifine. Butenafine also generates low MICs for Cryptococcus neoformans and Aspergillus spp. as well.
Lotrimin_Ultra Absorption
The total amount absorbed through the skin into the systemic circulation has not been quantified.
Lotrimin_Ultra Toxicity
No information avaliable
Lotrimin_Ultra Patient Information
Lotrimin_Ultra Organisms Affected
Fungi
