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Liponorm
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Liponorm Brand names, Liponorm Analogs

Liponorm Brand Names Mixture

  • No information avaliable

Liponorm Chemical_Formula

C25H38O5

Liponorm RX_link

http://www.rxlist.com/cgi/generic/simva.htm

Liponorm fda sheet

Liponorm FDA

Liponorm msds (material safety sheet)

Liponorm Synthesis Reference

W. F. Hoffman et al., U.S. Pat. 4,444,784 (1984)

Liponorm Molecular Weight

418.566 g/mol

Liponorm Melting Point

135-138oC

Liponorm H2O Solubility

0.76 mg/L

Liponorm State

Solid

Liponorm LogP

4.937

Liponorm Dosage Forms

Tablet (oral)

Liponorm Indication

For the treatment of hypercholesterolemia.

Liponorm Pharmacology

Simvastatin, the methylated form of lovastatin, is an oral antilipemic agent which inhibits HMG-CoA reductase. simvastatin is used in the treatment of primary hypercholesterolemia and is effective in reducing total and LDL-cholesterol as well as plasma triglycerides and apolipoprotein B.

Liponorm Absorption

Absorption of simvastatin, estimated relative to an intravenous reference dose, in each of two animal species tested, averaged about 85% of an oral dose. In animal studies, after oral dosing, simvastatin achieved substantially higher concentrations in the liver than in non-target tissues.

Liponorm side effects and Toxicity

No information avaliable

Liponorm Patient Information

Patients should be advised about substances they should not take concomitantly with simvastatin and be advised to report promptly unexplained muscle pain, tenderness, or weakness. Patients should also be advised to inform other physicians prescribing a new medication that they are taking ZOCOR.

Liponorm Organisms Affected

Humans and other mammals