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Levoxacin
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Levoxacin Brand names, Levoxacin Analogs

Levoxacin Brand Names Mixture

  • No information avaliable

Levoxacin Chemical_Formula

C36H42F2N6O9

Levoxacin RX_link

http://www.rxlist.com/cgi/generic2/quixin.htm

Levoxacin fda sheet

Levoxacin FDA

Levoxacin msds (material safety sheet)

Levoxacin Synthesis Reference

Mitscher, Lester A. et al.; J.Med.Chem.; 30; 12; 2283-2286(1987)

Levoxacin Molecular Weight

740.751 g/mol

Levoxacin Melting Point

No information avaliable

Levoxacin H2O Solubility

Insoluble

Levoxacin State

Solid

Levoxacin LogP

1.268

Levoxacin Dosage Forms

Tablet; Liquid; Solution

Levoxacin Indication

For the treatment of bacterial conjunctivitis caused by susceptible strains of the following organisms: Corynebacterium species, Staphylococus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, Streptococcus (Groups C/F/G), Viridans group streptococci, Acinetobacter lwoffii, Haemophilus influenzae, Serratia marcescens.

Levoxacin Pharmacology

Levofloxacin, a fluoroquinolone antiinfective, is the optically active L-isomer of ofloxacin. Levofloxacin is used to treat bacterial conjunctivitis, sinusitis, chronic bronchitis, community-acquired pneumonia and pneumonia caused by penicillin-resistant strains of Streptococcus pneumoniae, skin and skin structure infections, complicated urinary tract infections and acute pyelonephritis.

Levoxacin Absorption

Absorption of ofloxacin after single or multiple doses of 200 to 400 mg is predictable, and the amount of drug absorbed increases proportionately with the dose.

Levoxacin side effects and Toxicity

Side effects include disorientation, dizziness, drowsiness, hot and cold flashes, nausea, slurring of speech, swelling and numbness in the face

Levoxacin Patient Information

PATIENT INFORMATION

While taking ofloxacin patient should be advised to:

— to drink fluids liberally;

— that mineral supplements, vitamins with iron or minerals, calcium- , aluminum-, or magnesium-based antacids, sucralfate or Videx®, (Didanosine), chewable/buffered tablets or the pediatric powder for oral solution should not be taken within the two-hour period before or within the two-hour period after taking ofloxacin;

— that ofloxacin can be taken without regard to meals;

— that ofloxacin may cause neurologic adverse effects (e. g. , dizziness, lightheadedness) and that patients should know how they react to ofloxacin before they operate an automobile or machinery or engage in activities requiring mental alertness and coordination;

— to discontinue treatment and inform their physician if they experience pain, inflammation, or rupture of a tendon, and to rest and refrain from exercise until the diagnosis of tendinitis or tendon rupture has been confidently excluded;

— that ofloxacin may be associated with hypersensitivity reactions, even following the first dose, to discontinue the drug at the first sign of a skin rash, hives or other skin reactions, a rapid heartbeat, difficulty in swallowing or breathing, any swelling suggesting angioedema (e. g. , swelling of the lips, tongue, face; tightness of the throat, hoarseness), or any other symptom of an allergic reaction

— to avoid excessive sunlight or artificial ultraviolet light while receiving ofloxacin and to discontinue therapy if phototoxicity (e. g. , skin eruption) occurs;

— that if they are diabetic and are being treated with insulin or an oral hypoglycemic drug, to discontinue ofloxacin immediately if a hypoglycemic reaction occurs and consult a physician;

— that convulsions have been reported in patients taking quinolones, including ofloxacin, and to notify their physician before taking this drug if there is a history of this condition.

Levoxacin Organisms Affected

Enteric bacteria and other eubacteria