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Levitra Brand names, Levitra Analogs

Levitra Brand Names Mixture

  • No information avaliable

Levitra Chemical_Formula

C23H32N6O4S

Levitra RX_link

http://www.rxlist.com/cgi/generic3/levitra.htm

Levitra fda sheet

Levitra FDA

Levitra msds (material safety sheet)

Levitra Synthesis Reference

No information avaliable

Levitra Molecular Weight

488.604 g/mol

Levitra Melting Point

192 oC

Levitra H2O Solubility

0.11 mg/mL (HCl salt)

Levitra State

Solid

Levitra LogP

No information avaliable

Levitra Dosage Forms

Tablet (5, 10, and 20 mg)

Levitra Indication

Used for the treatment of erectile dysfunction

Levitra Pharmacology

Vardenafil is used to treat male erectile dysfunction (impotence) and pulmonary arterial hypertension (PAH). Part of the physiological process of erection involves the release of nitric oxide (NO) in the corpus cavernosum. This then activates the enzyme guanylate cyclase which results in increased levels of cyclic guanosine monophosphate (cGMP), leading to smooth muscle relaxation in the corpus cavernosum, resulting in increased inflow of blood and an erection. Vardenafil is a potent and selective inhibitor of cGMP specific phosphodiesterase type 5 (PDE5) which is responsible for degradation of cGMP in the corpus cavernosum. This means that, with vardenafil on board, normal sexual stimulation leads to increased levels of cGMP in the corpus cavernosum which leads to better erections. Without sexual stimulation and no activation of the NO/cGMP system, vardenafil should not cause an erection.

Levitra Absorption

Vardenafil is rapidly absorbed with absolute bioavailability of approximately 15%.

Levitra side effects and Toxicity

Symptoms of overdose include vision changes and back and muscle pain.

Levitra Patient Information

Levitra Organisms Affected

Humans and other mammals