Levamisole

Category

Levamisole




Useful info

Levamisole Brand names, Levamisole Analogs

Levamisole Brand Names Mixture

  • No information avaliable

    • Levamisole Chemical_Formula

    C11H12N2S

    Levamisole RX_link

    http://www.rxlist.com/cgi/generic3/levamisole.htm

    Levamisole fda sheet

    Levamisole FDA

    Levamisole msds (material safety sheet)

    Levamisole MSDS

    Levamisole Synthesis Reference

    No information avaliable

    Levamisole Molecular Weight

    204.292 g/mol

    Levamisole Melting Point

    264-265 oC

    Levamisole H2O Solubility

    210 mg/mL

    Levamisole State

    Solid

    Levamisole LogP

    2.046

    Levamisole Dosage Forms

    Tablet

    Levamisole Indication

    For adjuvant treatment in combination with fluorouracil after surgical resection in patients with Dukes' stage C colon cancer. Also used to treat malignant melanoma and head/neck cancer.

    Levamisole Pharmacology

    Levamisole is a synthetic imidazothiazole derivative that has been widely used in treatment of worm infestations in both humans and animals. As an anthelmintic, it probably works by targeting the nematode nicotinergic acetylcholine receptor. As an immunomodulator, it appears that Levamisole is an immunostimulant which has been shown to increase NK cells and activated T-cells in patients receiving this adjuvantly along with 5FU for Stage III colon cancer.

    Levamisole Absorption

    Levamisole is rapidly absorbed (2 hours) from the gastrointestinal tract.

    Levamisole Toxicity

    LD50 = 40 mg/kg (Pigs, subcutaneous); LD50 = 180 mg/kg (rat, oral)

    Levamisole Patient Information

    http://www.drugs.com/MTM/letrozole.html

    Levamisole Organisms Affected

    Humans and other mammals