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Levamisole Brand names, Levamisole Analogs

Levamisole Brand Names Mixture

  • No information avaliable

Levamisole Chemical_Formula

C11H12N2S

Levamisole RX_link

http://www.rxlist.com/cgi/generic3/levamisole.htm

Levamisole fda sheet

Levamisole FDA

Levamisole msds (material safety sheet)

Levamisole MSDS

Levamisole Synthesis Reference

No information avaliable

Levamisole Molecular Weight

204.292 g/mol

Levamisole Melting Point

264-265 oC

Levamisole H2O Solubility

210 mg/mL

Levamisole State

Solid

Levamisole LogP

2.046

Levamisole Dosage Forms

Tablet

Levamisole Indication

For adjuvant treatment in combination with fluorouracil after surgical resection in patients with Dukes' stage C colon cancer. Also used to treat malignant melanoma and head/neck cancer.

Levamisole Pharmacology

Levamisole is a synthetic imidazothiazole derivative that has been widely used in treatment of worm infestations in both humans and animals. As an anthelmintic, it probably works by targeting the nematode nicotinergic acetylcholine receptor. As an immunomodulator, it appears that Levamisole is an immunostimulant which has been shown to increase NK cells and activated T-cells in patients receiving this adjuvantly along with 5FU for Stage III colon cancer.

Levamisole Absorption

Levamisole is rapidly absorbed (2 hours) from the gastrointestinal tract.

Levamisole side effects and Toxicity

LD50 = 40 mg/kg (Pigs, subcutaneous); LD50 = 180 mg/kg (rat, oral)

Levamisole Patient Information

http://www.drugs.com/MTM/letrozole.html

Levamisole Organisms Affected

Humans and other mammals