L-Methyl Dopa en es it fr

L-Methyl Dopa Brand names, L-Methyl Dopa Analogs

L-Methyl Dopa Brand Names Mixture

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L-Methyl Dopa Chemical_Formula


L-Methyl Dopa RX_link


L-Methyl Dopa fda sheet

L-Methyl_Dopa FDA

L-Methyl Dopa msds (material safety sheet)

L-Methyl_Dopa MSDS

L-Methyl Dopa Synthesis Reference

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L-Methyl Dopa Molecular Weight

1270.28 g/mol

L-Methyl Dopa Melting Point

No information avaliable

L-Methyl Dopa H2O Solubility

Freely soluble as sodium salt (> 200mg/mL)

L-Methyl Dopa State


L-Methyl Dopa LogP

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L-Methyl Dopa Dosage Forms

Powder for solution (for injection)

L-Methyl Dopa Indication

For use in the treatment of patients with esophageal candidiasis and prophylaxis of Candida infections in patients undergoing hematopoietic stem cell transplantation.

L-Methyl Dopa Pharmacology

Formerly known as FK463, micafungin is a novel antifungal agent. It is a glucan synthesis inhibitor of the echinocandin structural class. The U.S. Food and Drug Administration approved micafungin in March 2005. Micafungin inhibits an enzyme essential for fungal cell-wall synthesis and is fungicidal (lethal) for Candida. Micafungin can be used concomitantly with a variety of other drugs, including the HIV protease inhibitor ritonavir and the transplant medications cyclosporine and tacrolimus.

L-Methyl Dopa Absorption

No information avaliable

L-Methyl Dopa side effects and Toxicity

Intravenous LD50 in rats is 125mg/kg. In dogs it is >200mg/kg. No cases of overdosage have been reported. Repeated daily doses up to 8 mg/kg (maximum total dose of 896 mg) in adult patients have been administered in clinical trials with no reported dose-limiting toxicity. The minimum lethal dose is 125 mg/kg in rats, equivalent to 8.1 times the recommended human clinical dose for esophageal candidiasis based on body surface area comparisons.

L-Methyl Dopa Patient Information

No information avaliable

L-Methyl Dopa Organisms Affected

Aspergillis, Candida and other fungi