L-Hyoscyamine
L-Hyoscyamine Brand names, L-Hyoscyamine Analogs
L-Hyoscyamine Brand Names Mixture
- No information avaliable
L-Hyoscyamine Chemical_Formula
C17H23NO3
L-Hyoscyamine RX_link
http://www.rxlist.com/cgi/generic/hyoscy.htm
L-Hyoscyamine fda sheet
L-Hyoscyamine msds (material safety sheet)
L-Hyoscyamine Synthesis Reference
Fodor et al., Acta Chem. Acad. Sci. Hung.28(4), 409 (1961)
L-Hyoscyamine Molecular Weight
289.369 g/mol
L-Hyoscyamine Melting Point
141oC
L-Hyoscyamine H2O Solubility
3.56 mg/mL
L-Hyoscyamine State
Solid
L-Hyoscyamine LogP
2.904
L-Hyoscyamine Dosage Forms
Tablets; Oral drops; Elixir; Injection
L-Hyoscyamine Indication
For treatment of bladder spasms, peptic ulcer disease, diverticulitis, colic, irritable bowel syndrome, cystitis, and pancreatitis. Also used to treat certain heart conditions, to control the symptoms of Parkinson's disease and rhinitis.
L-Hyoscyamine Pharmacology
L-Hyoscyamine, the active optical isomer of atropine (dl-hyoscyamine), is a tertiary amine anticholinergic gastrointestinal agent.
L-Hyoscyamine Absorption
Absorbed totally and completely by sublingual administration as well as oral administration.
L-Hyoscyamine side effects and Toxicity
Symptoms of overdose include headache, nausea, vomiting, blurred vision, dilated pupils, hot dry skin, dizziness, dryness of the mouth, difficulty in swallowing, and CNS stimulation. LD50=mg/kg(orally in rat)
L-Hyoscyamine Patient Information
L-Hyoscyamine Organisms Affected
Humans and other mammals
