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Konakion Brand names, Konakion Analogs

Konakion Brand Names Mixture

  • No information avaliable

Konakion Chemical_Formula

C31H46O2

Konakion RX_link

http://www.rxlist.com/cgi/generic3/phytonadione.htm

Konakion fda sheet

Konakion msds (material safety sheet)

Konakion Synthesis Reference

No information avaliable

Konakion Molecular Weight

450.696 g/mol

Konakion Melting Point

-20 oC

Konakion H2O Solubility

Insoluble in water

Konakion State

Liquid

Konakion LogP

8.841

Konakion Dosage Forms

Liquid

Konakion Indication

For the treatment of haemorrhagic conditions in infants, antidote for coumarin anticoagulants in hypoprothrombinaemia

Konakion Pharmacology

Phytonadione is a vitamin, indicated in the treatment of coagulation disorders which are due to faulty formation of factors II, VII, IX and X when caused by vitamin K deficiency or interference with vitamin K activity. Phytonadione aqueous colloidal solution of vitamin K1 for parenteral injection, possesses the same type and degree of activity as does naturally-occurring vitamin K, which is necessary for the production via the liver of active prothrombin (factor II), proconvertin (factor VII), plasma thromboplastin component (factor IX), and Stuart factor (factor X).

Konakion Absorption

Oral phytonadione is adequately absorbed from the gastrointestinal tract only if bile salts are present. After absorption, phytonadione is initially concentrated in the liver, but the concentration declines rapidly. Very little vitamin K accumulates in tissues.

Konakion side effects and Toxicity

No information avaliable

Konakion Patient Information

No information avaliable

Konakion Organisms Affected

Humans and other mammals