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Ketrax
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Ketrax Brand names, Ketrax Analogs

Ketrax Brand Names Mixture

  • No information avaliable

Ketrax Chemical_Formula

C16H20FN3O4

Ketrax RX_link

http://www.rxlist.com/cgi/generic3/linezolid.htm

Ketrax fda sheet

Ketrax FDA

Ketrax msds (material safety sheet)

Ketrax MSDS

Ketrax Synthesis Reference

No information avaliable

Ketrax Molecular Weight

337.346 g/mol

Ketrax Melting Point

No information avaliable

Ketrax H2O Solubility

3 mg/mL

Ketrax State

Solid

Ketrax LogP

0.232

Ketrax Dosage Forms

Solution; Tablets

Ketrax Indication

For the treatment of bacterial infections caused by susceptible strains of vancomycin resistant Enterococcus faecium, Staphylococcal aureus (methicillin resistant and susceptible strains), Streptococcus pneumoniae, Streptococcus pyogenes, Streptococcus agalactiae.

Ketrax Pharmacology

Linezolid is a synthetic antibacterial agent of a new class of antibiotics, the oxazolidinones, which has clinical utility in the treatment of infections caused by aerobic Gram-positive bacteria. The in vitro spectrum of activity of linezolid also includes certain Gram-negative bacteria and anaerobic bacteria. Susceptible organisms include methicillin- and vancomycin-resistant staphylococci, vancomycin-resistant enterococci, penicillin-resistant pneumococci and anaerobes. Oxazolidinones inhibit protein synthesis by binding at the P site at the ribosomal 50S subunit. Resistance to other protein synthesis inhibitors does not affect oxazolidinone activity, however rare development of oxazolidinone resistance cases, associated with 23S rRNA alterations during treatment have been reported. Linezolid inhibits bacterial protein synthesis through a mechanism of action different from that of other antibacterial agents; therefore, cross-resistance between linezolid and other classes of antibiotics is unlikely.

Ketrax Absorption

Linezolid is rapidly and extensively absorbed after oral dosing. Maximum plasma concentrations are reached approximately 1 to 2 hours after dosing, and the absolute bioavailability is approximately 100%.

Ketrax side effects and Toxicity

Clinical signs of acute toxicity lead to decreased activity, ataxia, vomiting and tremors.

Ketrax Patient Information

Ketrax Organisms Affected

Gram negative and gram positive bacteria