Ketotifene_[INN-French]

Category

Ketotifene_[INN-French]




Useful info

Ketotifene_[INN-French] Brand names, Ketotifene_[INN-French] Analogs

Ketotifene_[INN-French] Brand Names Mixture

  • No information avaliable

    • Ketotifene_[INN-French] Chemical_Formula

    C11H12N2S

    Ketotifene_[INN-French] RX_link

    http://www.rxlist.com/cgi/generic3/levamisole.htm

    Ketotifene_[INN-French] fda sheet

    Ketotifene_[INN-French] FDA

    Ketotifene_[INN-French] msds (material safety sheet)

    Ketotifene_[INN-French] MSDS

    Ketotifene_[INN-French] Synthesis Reference

    No information avaliable

    Ketotifene_[INN-French] Molecular Weight

    204.292 g/mol

    Ketotifene_[INN-French] Melting Point

    264-265 oC

    Ketotifene_[INN-French] H2O Solubility

    210 mg/mL

    Ketotifene_[INN-French] State

    Solid

    Ketotifene_[INN-French] LogP

    2.046

    Ketotifene_[INN-French] Dosage Forms

    Tablet

    Ketotifene_[INN-French] Indication

    For adjuvant treatment in combination with fluorouracil after surgical resection in patients with Dukes' stage C colon cancer. Also used to treat malignant melanoma and head/neck cancer.

    Ketotifene_[INN-French] Pharmacology

    Levamisole is a synthetic imidazothiazole derivative that has been widely used in treatment of worm infestations in both humans and animals. As an anthelmintic, it probably works by targeting the nematode nicotinergic acetylcholine receptor. As an immunomodulator, it appears that Levamisole is an immunostimulant which has been shown to increase NK cells and activated T-cells in patients receiving this adjuvantly along with 5FU for Stage III colon cancer.

    Ketotifene_[INN-French] Absorption

    Levamisole is rapidly absorbed (2 hours) from the gastrointestinal tract.

    Ketotifene_[INN-French] Toxicity

    LD50 = 40 mg/kg (Pigs, subcutaneous); LD50 = 180 mg/kg (rat, oral)

    Ketotifene_[INN-French] Patient Information

    http://www.drugs.com/MTM/letrozole.html

    Ketotifene_[INN-French] Organisms Affected

    Humans and other mammals