Ketoconazolum [Inn-Latin]

Ketoconazolum [Inn-Latin] Brand names, Ketoconazolum [Inn-Latin] Analogs

Ketoconazolum [Inn-Latin] Brand Names Mixture

No information avaliable

Ketoconazolum [Inn-Latin] Chemical_Formula

C₂₆H₂₈Cl₂N₄O₄

Ketoconazolum [Inn-Latin] RX_link

http://www.rxlist.com/cgi/generic/ketocon.htm

Ketoconazolum [Inn-Latin] fda sheet

Ketoconazolum_[Inn-Latin] FDA

Ketoconazolum [Inn-Latin] msds (material safety sheet)

Ketoconazolum_[Inn-Latin] MSDS

Ketoconazolum [Inn-Latin] Synthesis Reference

J. Heeres et al., U.S. Pat. 4,144,346 (1979)

Ketoconazolum [Inn-Latin] Molecular Weight

531.43 g/mol

Ketoconazolum [Inn-Latin] Melting Point

146 ^oC

Ketoconazolum [Inn-Latin] H₂O Solubility

0.0866 mg/L

Ketoconazolum [Inn-Latin] State

Solid

Ketoconazolum [Inn-Latin] LogP

3.651

Ketoconazolum [Inn-Latin] Dosage Forms

Tablets; Shampoo; Cream; Suspension

Ketoconazolum [Inn-Latin] Indication

For the treatment of the following systemic fungal infections: candidiasis, chronic mucocutaneous candidiasis, oral thrush, candiduria, blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis.

Ketoconazolum [Inn-Latin] Pharmacology

Ketoconazole, like clotrimazole, fluconazole, itraconazole, and miconazole, is an imidazole antifungal agent.

Ketoconazolum [Inn-Latin] Absorption

Moderate

Ketoconazolum [Inn-Latin] side effects and Toxicity

Hepatotoxicity, LD₅₀=86 mg/kg (orally in rat)

Ketoconazolum [Inn-Latin] Patient Information

Shampoo: May be irritating to mucous membranes of the eyes and contact with this area should be avoided.

There have been reports that use of the shampoo resulted in removal of the curl from permanently waved hair.

Tablet: Patients should be instructed to report any signs and symptoms which may suggest liver dysfunction so that appropriate biochemical testing can be done. Such signs and symptoms may include unusual fatigue, anorexia, nausea and/or vomiting, jaundice, dark urine or pale stools

Ketoconazolum [Inn-Latin] Organisms Affected

Fungi