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Kerastick Brand names, Kerastick Analogs

Kerastick Brand Names Mixture

  • No information avaliable

Kerastick Chemical_Formula

C5H9NO3

Kerastick RX_link

http://www.rxlist.com/cgi/generic3/levulan.htm

Kerastick fda sheet

Kerastick FDA

Kerastick msds (material safety sheet)

Kerastick MSDS

Kerastick Synthesis Reference

No information avaliable

Kerastick Molecular Weight

131.13 g/mol

Kerastick Melting Point

156-158 oC

Kerastick H2O Solubility

Very soluble

Kerastick State

Solid

Kerastick LogP

-1.363

Kerastick Dosage Forms

Two component system consisting of a plastic tube containing two sealed glass ampules and an applicator tip (one ampule contains 1.5 mL of solution vehicle, the other ampule contains 354 mg of aminolevulinic acid hcl as a dry solid)

Kerastick Indication

Aminolevulinic acid plus blue light illumination using a blue light photodynamic therapy illuminator is indicated for the treatment of minimally to moderately thick actinic keratoses of the face or scalp.

Kerastick Pharmacology

The metabolism of aminolevulinic acid (ALA) is the first step in the biochemical pathway resulting in heme synthesis. Aminolevulinic acid is not a photosensitizer, but rather a metabolic precursor of protoporphyrin IX (PpIX), which is a photosensitizer. The synthesis of ALA is normally tightly controlled by feedback inhibition of the enzyme, ALA synthetase, presumably by intracellular heme levels. ALA, when provided to the cell, bypasses this control point and results in the accumulation of PpIX, which is converted into heme by ferrochelatase through the addition of iron to the PpIX nucleus.

Kerastick Absorption

Oral bioavailability is 50-60%.

Kerastick side effects and Toxicity

Solution overdose have not been reported.

Kerastick Patient Information

Kerastick Organisms Affected

Humans and other mammals