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Kephton Brand names, Kephton Analogs

Kephton Brand Names Mixture

  • No information avaliable

Kephton Chemical_Formula

C31H46O2

Kephton RX_link

http://www.rxlist.com/cgi/generic3/phytonadione.htm

Kephton fda sheet

Kephton msds (material safety sheet)

Kephton Synthesis Reference

No information avaliable

Kephton Molecular Weight

450.696 g/mol

Kephton Melting Point

-20 oC

Kephton H2O Solubility

Insoluble in water

Kephton State

Liquid

Kephton LogP

8.841

Kephton Dosage Forms

Liquid

Kephton Indication

For the treatment of haemorrhagic conditions in infants, antidote for coumarin anticoagulants in hypoprothrombinaemia

Kephton Pharmacology

Phytonadione is a vitamin, indicated in the treatment of coagulation disorders which are due to faulty formation of factors II, VII, IX and X when caused by vitamin K deficiency or interference with vitamin K activity. Phytonadione aqueous colloidal solution of vitamin K1 for parenteral injection, possesses the same type and degree of activity as does naturally-occurring vitamin K, which is necessary for the production via the liver of active prothrombin (factor II), proconvertin (factor VII), plasma thromboplastin component (factor IX), and Stuart factor (factor X).

Kephton Absorption

Oral phytonadione is adequately absorbed from the gastrointestinal tract only if bile salts are present. After absorption, phytonadione is initially concentrated in the liver, but the concentration declines rapidly. Very little vitamin K accumulates in tissues.

Kephton side effects and Toxicity

No information avaliable

Kephton Patient Information

No information avaliable

Kephton Organisms Affected

Humans and other mammals