Kefroxil
Category
Kefroxil Brand names, Kefroxil Analogs
Kefroxil Brand Names Mixture
Kefroxil Chemical_Formula
C16H17N3O5S
Kefroxil RX_link
http://www.rxlist.com/cgi/generic/cefadrox.htm
Kefroxil fda sheet
Kefroxil msds (material safety sheet)
Kefroxil Synthesis Reference
L. B. Crast, Jr., U.S. Pat. 3,489,752 (1969)
Kefroxil Molecular Weight
363.389 g/mol
Kefroxil Melting Point
197oC
Kefroxil H2O Solubility
1110 mg/L
Kefroxil State
Solid
Kefroxil LogP
-0.355
Kefroxil Dosage Forms
Capsule; Tablet; Oral liquid
Kefroxil Indication
For the treatment of the following infections (skin, UTI, ENT) caused by; S. pneumoniae, H. influenzae, staphylococci, S. pyogenes (group A beta-hemolytic streptococci), E. coli, P. mirabilis, Klebsiella sp, coagulase-negative staphylococci and Streptococcus pyogenes
Kefroxil Pharmacology
Cefadroxil, a first-generation cephalosporin antibiotic, is used to treat urinary tract infections, skin and skin structure infections, pharyngitis, and tonsillitis.
Kefroxil Absorption
Cefadroxil is well absorbed on oral administration; food does not interfere with its absorption.
Kefroxil side effects and Toxicity
Nausea, vomiting, diarrhoea, allergic rashes may occur
Kefroxil Patient Information
Patients should be counseled that intibacterial drugs including DURICEF should only be used to treat bacterial
infections. They do not treat viral infections (eg. the common cold). When DURICEF is prescribed to treat a bacterial
infection, patients should be told that although it is common to feel better early in the course of therapy, the
medication should be taken exactly as directed. Skipping doses or not completing the full course of therapy may (1)
decrease the effectiveness of the immediate treatment and (2) increase the likelyhood that bacteria will develop
resistance and will not be treatable by DURICEF or other antibacterial drugs in the future.
Kefroxil Organisms Affected
Enteric bacteria and other eubacteria
