K-Ject
Category
K-Ject Brand names, K-Ject Analogs
K-Ject Brand Names Mixture
No information avaliable
K-Ject Chemical_Formula
C31H46O2
K-Ject RX_link
http://www.rxlist.com/cgi/generic3/phytonadione.htm
K-Ject fda sheet
K-Ject msds (material safety sheet)
K-Ject Synthesis Reference
No information avaliable
K-Ject Molecular Weight
450.696 g/mol
K-Ject Melting Point
-20 oC
K-Ject H2O Solubility
Insoluble in water
K-Ject State
Liquid
K-Ject LogP
8.841
K-Ject Dosage Forms
Liquid
K-Ject Indication
For the treatment of haemorrhagic conditions in infants, antidote for coumarin anticoagulants in hypoprothrombinaemia
K-Ject Pharmacology
Phytonadione is a vitamin, indicated in the treatment of coagulation disorders which are due to faulty formation of factors II, VII, IX and X when caused by vitamin K deficiency or interference with vitamin K activity. Phytonadione aqueous colloidal solution of vitamin K1 for parenteral injection, possesses the same type and degree of activity as does naturally-occurring vitamin K, which is necessary for the production via the liver of active prothrombin (factor II), proconvertin (factor VII), plasma thromboplastin component (factor IX), and Stuart factor (factor X).
K-Ject Absorption
Oral phytonadione is adequately absorbed from the gastrointestinal tract only if bile salts are present. After absorption, phytonadione is initially concentrated in the liver, but the concentration declines rapidly. Very little vitamin K accumulates in tissues.
K-Ject Toxicity
No information avaliable
K-Ject Patient Information
No information avaliable
K-Ject Organisms Affected
Humans and other mammals
