Jenacyclin
Jenacyclin Brand names, Jenacyclin Analogs
Jenacyclin Brand Names Mixture
- No information avaliable
Jenacyclin Chemical_Formula
C22H24N2O8
Jenacyclin RX_link
http://www.rxlist.com/cgi/generic/doxycyc.htm
Jenacyclin fda sheet
Jenacyclin msds (material safety sheet)
Jenacyclin Synthesis Reference
C. R. Stephens et al.; J. Am. Chem. Soc. 80; 5324 (1958)
Jenacyclin Molecular Weight
444.435 g/mol
Jenacyclin Melting Point
201 oC
Jenacyclin H2O Solubility
630 mg/L
Jenacyclin State
Solid
Jenacyclin LogP
-1.219
Jenacyclin Dosage Forms
Tablet; Capsule; Gel; Liquid; Powder; Powder for solution
Jenacyclin Indication
For the treatment of the following infections:Rocky mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsialpox, and tick fevers caused by Rickettsiae, Chancroid caused by Haemophilus ducreyi, Uncomplicated gonorrhea caused by Neisseria gonorrhoeae, Respiratory tract infections caused by Mycoplasma pneumoniae or Streptococcus pneumoniae. Lymphogranuloma ve
Jenacyclin Pharmacology
Doxycycline, a long-acting tetracycline derived from oxytetracycline, is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with COPD, and adult periodontitis.
Jenacyclin Absorption
completely absorbed after oral administration
Jenacyclin side effects and Toxicity
anorexia, nausea, diarrhoea, glossitis, dysphagia, enterocolitis and inflammatory lesions (with monilial overgrowth) in the anogenital region. skin reactions such as maculopapular and erythematous rashes, exfoliative dermatitis, photosensitivity, hypersensitivity reactions such as urticaria, angioneurotic oedema, anaphylaxis, anaphyl-actoid purpura, pericarditis, and exacerbation of systemic lupus erythematosus, benign intracranial hypertension in adults disappearing on discontinuation of the medicine, haematologic abnormalities such as haemolytic anaemia, thrombocytopenia, neutropenia, and eosinophilia. LD50=262 mg/kg(i.p. in rat)
Jenacyclin Patient Information
Jenacyclin Organisms Affected
Enteric bacteria and other eubacteria
