Ismelin

Ismelin Brand names, Ismelin Analogs

Ismelin Brand Names Mixture

No information avaliable

Ismelin Chemical_Formula

C₁₀H₂₂N₄

Ismelin RX_link

No information avaliable

Ismelin fda sheet

Ismelin msds (material safety sheet)

Ismelin MSDS

Ismelin Synthesis Reference

No information avaliable

Ismelin Molecular Weight

198.309 g/mol

Ismelin Melting Point

250 ^oC (sulfate salt)

Ismelin H₂O Solubility

Very soluble

Ismelin State

Solid

Ismelin LogP

0.693

Ismelin Dosage Forms

Tablet

Ismelin Indication

For the treatment of moderate and severe hypertension, either alone or as an adjunct, and for the treatment of renal hypertension.

Ismelin Pharmacology

High blood pressure can cause the heart and arteries to not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled. Guanethidine works by decreasing the heart rate and relaxing the blood vessels so that blood can flow more easily through the body, thereby reducing these risks. It is a postganglionic sympathetic nerve terminal blocker that prevents the release of norepinephrine from nerve terminals.

Ismelin Absorption

3-30% of oral dose (poor and highly variable)

Ismelin side effects and Toxicity

Side effects include drowsiness, dizziness, tiredness or confusion. LD₅₀=1000 mg/kg (mouse, oral)

Ismelin Patient Information

http://www.drugs.com/cons/Guanadrel.html

Ismelin Organisms Affected

Humans and other mammals