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Indion Brand names, Indion Analogs

Indion Brand Names Mixture

  • No information avaliable

Indion Chemical_Formula

C15H10O2

Indion RX_link

No information avaliable

Indion fda sheet

Indion msds (material safety sheet)

Indion MSDS

Indion Synthesis Reference

No information avaliable

Indion Molecular Weight

222.239 g/mol

Indion Melting Point

148-151 oC

Indion H2O Solubility

27 mg/L (at 20 oC)

Indion State

Solid

Indion LogP

2.917

Indion Dosage Forms

Tablet

Indion Indication

For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.

Indion Pharmacology

Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.

Indion Absorption

Absorbed slowly from the gastrointestinal tract.

Indion side effects and Toxicity

Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.

Indion Patient Information

No information avaliable

Indion Organisms Affected

Humans and other mammals