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Indema Brand names, Indema Analogs

Indema Brand Names Mixture

  • No information avaliable

Indema Chemical_Formula

C15H10O2

Indema RX_link

No information avaliable

Indema fda sheet

Indema msds (material safety sheet)

Indema MSDS

Indema Synthesis Reference

No information avaliable

Indema Molecular Weight

222.239 g/mol

Indema Melting Point

148-151 oC

Indema H2O Solubility

27 mg/L (at 20 oC)

Indema State

Solid

Indema LogP

2.917

Indema Dosage Forms

Tablet

Indema Indication

For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.

Indema Pharmacology

Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.

Indema Absorption

Absorbed slowly from the gastrointestinal tract.

Indema side effects and Toxicity

Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.

Indema Patient Information

No information avaliable

Indema Organisms Affected

Humans and other mammals