Ifex/Mesnex Kit en es it fr

Ifex/Mesnex Kit Brand names, Ifex/Mesnex Kit Analogs

Ifex/Mesnex Kit Brand Names Mixture

  • No information avaliable

Ifex/Mesnex Kit Chemical_Formula

C7H15Cl2N2O2P

Ifex/Mesnex Kit RX_link

http://www.rxlist.com/cgi/generic2/ifosfamide.htm

Ifex/Mesnex Kit fda sheet

http://www.accessdata.fda.gov/scripts/cder/onctools/summary.cfm?ID=95

Ifex/Mesnex Kit msds (material safety sheet)

Ifex/Mesnex_Kit MSDS

Ifex/Mesnex Kit Synthesis Reference

No information avaliable

Ifex/Mesnex Kit Molecular Weight

261.085 g/mol

Ifex/Mesnex Kit Melting Point

39-41 oC

Ifex/Mesnex Kit H2O Solubility

3780 mg/L

Ifex/Mesnex Kit State

Solid

Ifex/Mesnex Kit LogP

-0.01

Ifex/Mesnex Kit Dosage Forms

Powder for constitution and administration by intravenous infusion

Ifex/Mesnex Kit Indication

For third line chemotherapy of germ cell testicular cancer. It should ordinarily be used in combination with a prophylactic agent for hemorrhagic cystitis, such as mesna.

Ifex/Mesnex Kit Pharmacology

Ifosfamide selectively inhibits the synthesis of deoxyribonucleic acid (DNA). The guanine and cytosine content correlates with the degree of ifosfamide-induced cross-linking. At high concentrations of the drug, cellular RNA and protein synthesis are also suppressed.

Ifex/Mesnex Kit Absorption

No information avaliable

Ifex/Mesnex Kit side effects and Toxicity

LD50 (mouse) = 390-1005 mg/kg, LD50 (rat) = 150-190 mg/kg. Side effects include nausea, vomiting and myelosuppression. Toxic effects include central nervous system toxicity (confusion, hallucinations) and urotoxic effects (cystitis, blood in urine).

Ifex/Mesnex Kit Patient Information

No information avaliable

Ifex/Mesnex Kit Organisms Affected

Humans and other mammals