Ifenec
Category
Ifenec Brand names, Ifenec Analogs
Ifenec Brand Names Mixture
Ifenec Chemical_Formula
C12H15N5O3
Ifenec RX_link
http://www.rxlist.com/cgi/generic4/baraclude.htm
Ifenec fda sheet
Ifenec msds (material safety sheet)
Ifenec Synthesis Reference
No information avaliable
Ifenec Molecular Weight
277.279 g/mol
Ifenec Melting Point
No information avaliable
Ifenec H2O Solubility
Slightly soluble (2.4 mg/mL at pH 7.9, 25oC)
Ifenec State
Solid
Ifenec LogP
No information avaliable
Ifenec Dosage Forms
Film-coated tablets for oral administration (0.5 mg, 1 mg); Oral solution (0.05 mg/mL)
Ifenec Indication
For the treatment of chronic hepatitis B virus infection in adults with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease.
Ifenec Pharmacology
Entecavir is a guanosine nucleoside analogue with selective activity against hepatitis B virus (HBV). It is designed to selectively inhibit the Hepatitis B virus, blocking all three steps in the replication process. Entecavir is more efficient than an older Hepatitis B drug, lamivudine.
Ifenec Absorption
Absorption Following oral administration in healthy subjects, entecavir peak plasma concentrations occurred between 0.5 and 1.5 hours. In healthy subjects, the bioavailability of the tablet is 100% relative to the oral solution.
Ifenec side effects and Toxicity
No information avaliable
Ifenec Patient Information
Ifenec Organisms Affected
Hepatitis B
