Ibutilidum [INN-Latin] en es it fr

Ibutilidum [INN-Latin] Brand names, Ibutilidum [INN-Latin] Analogs

Ibutilidum [INN-Latin] Brand Names Mixture

  • No information avaliable

Ibutilidum [INN-Latin] Chemical_Formula

C20H36N2O3S

Ibutilidum [INN-Latin] RX_link

http://www.rxlist.com/cgi/generic3/ibutilide.htm

Ibutilidum [INN-Latin] fda sheet

Ibutilidum_[INN-Latin] FDA

Ibutilidum [INN-Latin] msds (material safety sheet)

Ibutilidum [INN-Latin] Synthesis Reference

No information avaliable

Ibutilidum [INN-Latin] Molecular Weight

384.578 g/mol

Ibutilidum [INN-Latin] Melting Point

No information avaliable

Ibutilidum [INN-Latin] H2O Solubility

100 mg/mL

Ibutilidum [INN-Latin] State

Solid

Ibutilidum [INN-Latin] LogP

5.756

Ibutilidum [INN-Latin] Dosage Forms

Solution (for injection); Suspension

Ibutilidum [INN-Latin] Indication

Indicated for the rapid conversion of atrial fibrillation or atrial flutter of recent onset to sinus rhythm.

Ibutilidum [INN-Latin] Pharmacology

Ibutilide fumurate prolongs the action potential duration and increases both atrial and ventricular refractoriness in vivo, i.e., class III electrophysiologic effects. Voltage clamp studies indicate that Ibutilide, at nanomolar concentrations, delays repolarization by activation of a slow, inward current (predominantly sodium), rather than by blocking outward potassium currents, which is the mechanism by which most other class III antiarrhythmics act.

Ibutilidum [INN-Latin] Absorption

Rapid after intravenous injection

Ibutilidum [INN-Latin] side effects and Toxicity

No information avaliable

Ibutilidum [INN-Latin] Patient Information

No information avaliable

Ibutilidum [INN-Latin] Organisms Affected

Humans and other mammals