Hydromedin

• Diuretics
• Enzyme Inhibitors

• Crinuryl
• Edecril
• Edecrin
• Edecrina
• Endecril
• Etacrinic acid
• Etacrynic acid
• Etakrinic acid
• Ethacrynate
• Ethacrynic acid (USAN)
• Hidromedin
• Hydromedin
• Methylenebutyrylphenoxyacetic acid
• Mingit
• Otacril
• Reomax
• Taladren
• Uregit

• No information avaliable

C₁₃H₁₂Cl₂O₄

http://www.rxlist.com/cgi/generic3/edecrin.htm

Hydromedin FDA

Hydromedin MSDS

No information avaliable

303.137 g/mol

122.5 ^oC

No information avaliable

Solid

3.414

Tablet (25, 50 mg); Powder for solution

For the treatment of high blood pressure and edema caused by diseases like congestive heart failure, liver failure, and kidney failure.

Ethacrynic acid is a monosulfonamyl loop or high ceiling diuretic. Ethacrynic acid acts on the ascending limb of the loop of Henle and on the proximal and distal tubules. Urinary output is usually dose dependent and related to the magnitude of fluid accumulation. Water and electrolyte excretion may be increased several times over that observed with thiazide diuretics, since ethacrynic acid inhibits reabsorption of a much greater proportion of filtered sodium than most other diuretic agents. Therefore, ethacrynic acid is effective in many patients who have significant degrees of renal insufficiency. Ethacrynic acid has little or no effect on glomerular filtration or on renal blood flow, except following pronounced reductions in plasma volume when associated with rapid diuresis.

Onset of action is rapid, usually within 30 minutes after an oral dose of ethacrynic acid or within 5 minutes after an intravenous injection of ethacrynic acid.

Overdosage may lead to excessive diuresis with electrolyte depletion.

No information avaliable

Humans and other mammals