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Hibisol
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Hibisol Brand names, Hibisol Analogs

Hibisol Brand Names Mixture

  • Agro Blue (Chlorhexidine Acetate + Glycerine)
  • Avagard Chg (Alcohol Anhydrous + Chlorhexidine Gluconate)
  • Baxedin 2% - 70% (Chlorhexidine Gluconate + Isopropyl Alcohol)
  • Bio Text - Liq Hos (Alcohol Anhydrous + Chlorhexidine Gluconate)
  • Biomers - Liq Ins (Alcohol Anhydrous + Chlorhexidine Gluconate)
  • Bioprep (Chlorhexidine Gluconate + Didecyl Dimethyl Ammonium Chloride)
  • Bioprep Liq (Chlorhexidine Gluconate + Didecyl Dimethyl Ammonium Chloride + Isopropyl Alcohol)
  • Biosurf - Liq Hos (Alcohol Anhydrous + Chlorhexidine Gluconate)
  • Boston Advance Comfort Formula Conditioning Solution (Chlorhexidine Gluconate + Disodium Edetate + Polyaminopropyl Biguanide)
  • Boston Conditioning Solution (Chlorhexidine Gluconate + Disodium Edetate)
  • Boston Simplicity Solution - Liquid (Chlorhexidine Gluconate + Edetic Acid + Polyaminopropyl Biguanide)
  • Boston Simplus Multi-Action Solution (Chlorhexidine Gluconate + Polyaminopropyl Biguanide)
  • Boston?Md Conditioning Solution (Chlorhexidine Gluconate + Disodium Edetate)
  • Burn O Sol Spray (Benzocaine + Chlorhexidine Acetate)
  • Centaur Light Lube Gel (Chlorhexidine + Ethyl Cellulose)
  • Chloraprep Liq 0.5% (Chlorhexidine Gluconate + Isopropyl Alcohol)
  • Chlorhexidine 0.5% Liq (Chlorhexidine Gluconate + Isopropyl Alcohol)
  • Chlorhexidine and Isopropyl Alcohol Prep Pads (Chlorhexidine Gluconate + Isopropyl Alcohol)
  • Chlorhexidine and Isopropyl Alcohol Swabsticks (Chlorhexidine Gluconate + Isopropyl Alcohol)
  • Chlorhexidine-Cetrimide Soltn Conc (Cetrimonium Bromide + Chlorhexidine Gluconate)
  • Cida-Stat Foam (Chlorhexidine Gluconate + Isopropyl Alcohol)
  • Cida-Stat Liq (Chlorhexidine Gluconate + Isopropyl Alcohol)
  • Comfortcare Wetting and Soaking Solution (Chlorhexidine Gluconate + Disodium Edetate)
  • Della-Blue Teat Dip Non-Iodine (Chlorhexidine Acetate + Glycerine)
  • Dexidin 0.5 Solution (Chlorhexidine Gluconate + Isopropyl Alcohol)
  • Eye and Wound Powder (Chlorhexidine Hydrochloride + Hydrocortisone Acetate + Penicillin G Procaine + Sulfathiazole)
  • Flamazine C (Chlorhexidine Gluconate + Silver Sulfadiazine)
  • Foam Care Chg Surgical Hand Scrub (Chlorhexidine Gluconate + Isopropyl Alcohol)
  • G2 (Alcohol Anhydrous + Chlorhexidine Gluconate)
  • Germi-Stat Prep Gel (Chlorhexidine Gluconate + Isopropyl Alcohol)
  • Hexifoam-Skin Disinfectant Aer 1% (Alcohol Anhydrous + Chlorhexidine Gluconate)
  • Hibistat Germicidal Hand Rinse (Chlorhexidine Gluconate + Isopropyl Alcohol)
  • Hx Dip (Post Milking Teat Dip) (Chlorhexidine Acetate + Glycerine)
  • Hx Dip Lv (Post Milking Teat Dip) (Chlorhexidine Acetate + Glycerine)
  • Ic-Gel (Chlorhexidine Gluconate + Isopropyl Alcohol)
  • Inhibidex (Chlorhexidine Acetate + Glycerine)
  • Lines (Alcohol Anhydrous + Chlorhexidine Gluconate)
  • Mediwipe Pad (Chlorhexidine Gluconate + Phenoxyethanol)
  • Ready Wipe (Alcohol Anhydrous + Chlorhexidine Acetate)
  • Roby F60 Chlorhexidine Teat Dip (Chlorhexidine Acetate + Glycerine)
  • Salvesept Crm (Cetrimonium Bromide + Chlorhexidine Gluconate)
  • Sanhexidine Liq (Chlorhexidine Acetate + Glycerine + Lanolin)
  • Sanidip (Chlorhexidine Acetate + Glycerine)
  • Sanifilm (Chlorhexidine Acetate + Glycerine)
  • Savlodil (Single Use) (Cetrimide + Chlorhexidine Gluconate)
  • Savlon Hospital Concentrate (Cetrimide + Chlorhexidine Gluconate)
  • Savlon Hospital Concentrate Disinf Liq (Cetrimonium Bromide + Chlorhexidine Gluconate)
  • Scrub-Stat Iv 4% (Chlorhexidine Gluconate + Isopropyl Alcohol)
  • Septefx (18.5%) (Alcohol Anhydrous + Chlorhexidine Gluconate + Edetic Acid)
  • Septefx (70.5%) (Alcohol Anhydrous + Chlorhexidine Gluconate + Edetic Acid)
  • Septi-San (Chlorhexidine Gluconate + Didecyl Dimethyl Ammonium Chloride)
  • Soft Care Antiseptic Hand Soap (Chlorhexidine Gluconate + Didecyl Dimethyl Ammonium Chloride)
  • Solu-I.V. Chg-Alcohol (Chlorhexidine Gluconate + Isopropyl Alcohol)
  • Solu-I.V. Tiges Montees Chd Alcool - Stk (Chlorhexidine Gluconate + Isopropyl Alcohol)
  • Solu-Iv Chd-Alcool Tampon (Chlorhexidine Gluconate + Isopropyl Alcohol)
  • Soluprep Chd-Alcohol-Spg-Liq (Chlorhexidine Gluconate + Isopropyl Alcohol)
  • Spectro Tar Antiseptic Shampoo (Chlorhexidine Gluconate + Coal Tar)
  • Stanhexidine 2% with Isopropyl Alcohol 4% (Chlorhexidine Gluconate + Isopropyl Alcohol)
  • Stanhexidine 4% with Isopropyl Alcohol 4% (Chlorhexidine Gluconate + Isopropyl Alcohol)
  • Stanhexidine Aqueous 2% with 4% Isopropyl Alcohol (Chlorhexidine Gluconate + Isopropyl Alcohol)
  • Stanhexidine Untinted Tincture 0.5% W Alco (Chlorhexidine Gluconate + Isopropyl Alcohol)
  • Steri-Stat Liq 4.0% (Chlorhexidine Gluconate + Isopropyl Alcohol)
  • Steri-Stat Tincture (Tinted) Antis Prep Gel (Chlorhexidine Gluconate + Isopropyl Alcohol)
  • Sterigel (Alcohol Anhydrous + Chlorhexidine Gluconate)
  • Stomadhex C-100 (Chlorhexidine Acetate + Nicotinamide)
  • Stomadhex C-300 (Chlorhexidine Acetate + Nicotinamide)
  • Swiffer Wetjet Antibacterial Floor Cleaner (Chlorhexidine Acetate + Didecyl Dimethyl Ammonium Chloride)
  • Ultra Dip (Chlorhexidine Acetate + Glycerine)
  • Ultra Dip Ext (Chlorhexidine Acetate + Glycerine)
  • Ultra Dip LV (Chlorhexidine Acetate + Glycerine)
  • Ultrastat (Chlorhexidine Hydrochloride + Sodium Alginate)

Hibisol Chemical_Formula

C22H30Cl2N10

Hibisol RX_link

http://www.rxlist.com/cgi/generic2/chlorhexidine.htm

Hibisol fda sheet

Hibisol FDA

Hibisol msds (material safety sheet)

Hibisol MSDS

Hibisol Synthesis Reference

Rose, Swain, J. Chem. Soc. 1956, 4422;U.S. Pat. 2,684,924(1954)

Hibisol Molecular Weight

505.446 g/mol

Hibisol Melting Point

134 oC

Hibisol H2O Solubility

0.08%(w/v)

Hibisol State

Solid

Hibisol LogP

4.066

Hibisol Dosage Forms

Oral rinse; Pellet (extended-release); Periochip (in a biodegradable matrix of hydrolyzed gelatin cross-linked with glutaraldehyde); Cream; Dressing; Gel; Lotion; Ointment; Sponge

Hibisol Indication

For reduction of pocket depth in patients with adult periodontitis, used as an adjunct to scaling and root planing procedures. Also for prevention of dental caries, oropharyngeal decontamination in critically ill patients, hand hygiene in health-care personnel, general skin cleanser, and catheter site preparation and care.

Hibisol Pharmacology

Chlorhexidine, a topical antimicrobial agent, is bactericidal. Because of its positive charge, the chlorhexidine molecule reacts with the microbial cell surface to destroy the integrity of the cell membrane. This novel mechanism of action makes it highly unlikely for the development of bacterial resistance.

Hibisol Absorption

Absorption of chlorhexidine from the gastrointestinal tract is very poor. Additionally, an in vivo study in 18 adult patients found no detectable plasma or urine chlorhexidine concentrations following insertion of four periodontal implants under clinical conditions.

Hibisol side effects and Toxicity

LD50= 2g/kg (human, oral); LD50= 3 g/kg (rat, oral); LD50= 2.5 g/kg (mice, oral); LD50= 21 mg/kg (male rat, IV); LD50= 23 mg/kg (female rat, IV); LD50= 25 mg/kg (male mice, IV); LD50= 24 mg/kg (female mice, IV); LD50= 1g/kg (rat, subcutaneous); LD50= 637 mg/kg (male mice, subcutaneous); LD50= 632 mg/kg (female mice, subcutaneous)

Hibisol Patient Information

Hibisol Organisms Affected

Bacteria