PharmacyCodes



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Hepitec Brand names, Hepitec Analogs

Hepitec Brand Names Mixture

  • Combivir (Lamivudine + Zidovudine)
  • Kivexa (Abacavir (Abacavir Sulfate) + Lamivudine)
  • Trizivir (Abacavir (Abacavir Sulfate) + Lamivudine + Zidovudine)

Hepitec Chemical_Formula

C8H11N3O3S

Hepitec RX_link

http://www.rxlist.com/cgi/generic3/lamivudine.htm

Hepitec fda sheet

Hepitec FDA

Hepitec msds (material safety sheet)

Hepitec MSDS

Hepitec Synthesis Reference

No information avaliable

Hepitec Molecular Weight

229.257 g/mol

Hepitec Melting Point

160-162 oC

Hepitec H2O Solubility

70 mg/ml

Hepitec State

Solid

Hepitec LogP

No information avaliable

Hepitec Dosage Forms

Solution; Tablet

Hepitec Indication

For the treatment of HIV infection and chronic hepatitis B (HBV).

Hepitec Pharmacology

Lamivudine is a nucleoside reverse transcriptase inhibitor (NRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV). Lamivudine is phosphorylated to active metabolites that compete for incorporation into viral DNA. They inhibit the HIV reverse transcriptase enzyme competitively and act as a chain terminator of DNA synthesis. The lack of a 3'-OH group in the incorporated nucleoside analogue prevents the formation of the 5' to 3' phosphodiester linkage essential for DNA chain elongation, and therefore, the viral DNA growth is terminated.

Hepitec Absorption

Lamivudine was rapidly absorbed after oral administration in HIV-infected patients. Absolute bioavailability in adults is 86% ± 16% for the tablet and 87% ± 13% for the oral solution.

Hepitec side effects and Toxicity

No information avaliable

Hepitec Patient Information

Hepitec Organisms Affected

Human immunodeficiency virus and Hepatitis B virus