Guanfacine HCl en es it fr

Guanfacine HCl Brand names, Guanfacine HCl Analogs

Guanfacine HCl Brand Names Mixture

  • No information avaliable

Guanfacine HCl Chemical_Formula

C9H9Cl2N3O

Guanfacine HCl RX_link

http://www.rxlist.com/cgi/generic3/guanfacine.htm

Guanfacine HCl fda sheet

Guanfacine HCl msds (material safety sheet)

Guanfacine HCl Synthesis Reference

J. B. Bream, C.W. Coward et al.; U.S. Pat. 3,632,645 (1972)

Guanfacine HCl Molecular Weight

246.093 g/mol

Guanfacine HCl Melting Point

225-227 oC

Guanfacine HCl H2O Solubility

1892 mg/L

Guanfacine HCl State

Solid

Guanfacine HCl LogP

2.464

Guanfacine HCl Dosage Forms

Tablet (oral)

Guanfacine HCl Indication

For use in the management of hypertension.

Guanfacine HCl Pharmacology

Similar to clonidine, guanfacine is a centrally-acting, alpha(2)-adrenergic receptor agonist used alone or in combination with other drugs for the treatment of hypertension.

Guanfacine HCl Absorption

Rapid and complete, with an oral bioavailability of approximately 80%.

Guanfacine HCl side effects and Toxicity

Symptoms of overdose include drowsiness, lethargy, bradycardia and hypotension. LD50=165mg/kg (orally in mice)

Guanfacine HCl Patient Information

Patients who receive guanfacine should be advised to exercise caution when operating dangerous machinery or driving motor vehicles until it is determined that they do not become drowsy or dizzy from the medication. Patients should be warned that their tolerance for alcohol and other CNS depressants may be diminished. Patients should be advised not to discontinue therapy abruptly.

Guanfacine HCl Organisms Affected

Humans and other mammals