Guanethidine Monosulfate
Guanethidine Monosulfate Brand names, Guanethidine Monosulfate Analogs
Guanethidine Monosulfate Brand Names Mixture
- No information avaliable
Guanethidine Monosulfate Chemical_Formula
C10H22N4
Guanethidine Monosulfate RX_link
No information avaliable
Guanethidine Monosulfate fda sheet
Guanethidine Monosulfate msds (material safety sheet)
Guanethidine Monosulfate Synthesis Reference
No information avaliable
Guanethidine Monosulfate Molecular Weight
198.309 g/mol
Guanethidine Monosulfate Melting Point
250 oC (sulfate salt)
Guanethidine Monosulfate H2O Solubility
Very soluble
Guanethidine Monosulfate State
Solid
Guanethidine Monosulfate LogP
0.693
Guanethidine Monosulfate Dosage Forms
Tablet
Guanethidine Monosulfate Indication
For the treatment of moderate and severe hypertension, either alone or as an adjunct, and for the treatment of renal hypertension.
Guanethidine Monosulfate Pharmacology
High blood pressure can cause the heart and arteries to not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled. Guanethidine works by decreasing the heart rate and relaxing the blood vessels so that blood can flow more easily through the body, thereby reducing these risks. It is a postganglionic sympathetic nerve terminal blocker that prevents the release of norepinephrine from nerve terminals.
Guanethidine Monosulfate Absorption
3-30% of oral dose (poor and highly variable)
Guanethidine Monosulfate side effects and Toxicity
Side effects include drowsiness, dizziness, tiredness or confusion. LD50=1000 mg/kg (mouse, oral)
Guanethidine Monosulfate Patient Information
http://www.drugs.com/cons/Guanadrel.html
Guanethidine Monosulfate Organisms Affected
Humans and other mammals
