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Gemfibril Brand names, Gemfibril Analogs

Gemfibril Brand Names Mixture

  • No information avaliable

Gemfibril Chemical_Formula

C15H22O3

Gemfibril RX_link

http://www.rxlist.com/cgi/generic/gemfib.htm

Gemfibril fda sheet

Gemfibril FDA

Gemfibril msds (material safety sheet)

Gemfibril Synthesis Reference

P. L. CREGER, U.S. Pat. 3,674,836 (1972)

Gemfibril Molecular Weight

250.333 g/mol

Gemfibril Melting Point

61-63 oC

Gemfibril H2O Solubility

10 mg/mL (in base)

Gemfibril State

Solid

Gemfibril LogP

4.242

Gemfibril Dosage Forms

Tablets; Capsules

Gemfibril Indication

For treatment of adult patients with very high elevations of serum triglyceride levels (types IV and V hyperlipidemia) who are at risk of developing pancreatitis (inflammation of the pancreas) and who do not respond adequately to a strict diet.

Gemfibril Pharmacology

Gemfibrozil, a fibric acid antilipemic agent similar to clofibrate, is used to treat hyperlipoproteinemia and as a second-line therapy for type IIb hypercholesterolemia. It acts to reduce triglyceride levels, reduce VLDL levels, reduce LDL levels (moderately), and increase HDL levels (moderately).

Gemfibril Absorption

Well absorbed from gastrointestinal tract (within 1-2 hours).

Gemfibril side effects and Toxicity

Oral, mouse: LD50 = 3162 mg/kg. Symptoms of overdose include abdominal cramps, diarrhea, joint and muscle pain, nausea, and vomiting.

Gemfibril Patient Information

Gemfibrozil is used to lower high triglyceride and cholesterol levels. Notify your physician if you are pregnant or nursing. Gemfibrozil should be taken 30 minutes before the morning and evening meals. This medication may cause dizziness or blurred vision; use caution while driving or operating hazardous machinery. Gemfibrozil may cause an increase in blood sugar. If you have diabetes mellitus, carefully monitor blood sugar levels. Notify your physician if you develop severe stomach pain, muscle pain or weakness, or unexplained fever.

Gemfibril Organisms Affected

Humans and other mammals