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Gardenal
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Gardenal Brand names, Gardenal Analogs

Gardenal Brand Names Mixture

  • No information avaliable

Gardenal Chemical_Formula

C12H12N2O3

Gardenal RX_link

No information avaliable

Gardenal fda sheet

Gardenal msds (material safety sheet)

Gardenal MSDS

Gardenal Synthesis Reference

Hoerlein, U.S. Pat. 1,025,872 (1912)

Gardenal Molecular Weight

232.235 g/mol

Gardenal Melting Point

174 oC

Gardenal H2O Solubility

<0.01 g/100 mL

Gardenal State

Solid

Gardenal LogP

1.777

Gardenal Dosage Forms

Tablet; Elixir

Gardenal Indication

For the treatment of Epilepsy

Gardenal Pharmacology

Phenobarbital, the longest-acting barbiturate, is used for its anticonvulsant and sedative-hypnotic properties in the management of all seizure disorders except absence (petit mal).

Gardenal Absorption

Absorbed in varying degrees following oral, rectal or parenteral administration. The salts are more rapidly absorbed than are the acids. The rate of absorption is increased if the sodium salt is ingested as a dilute solution or taken on an empty stomach

Gardenal side effects and Toxicity

CNS and respiratory depression which may progress to Cheyne-Stokes respiration, areflexia, constriction of the pupils to a slight degree (though in severe poisoning they may wshow paralytic dilation), oliguria, tachycardia, hypotension, lowered body temperature, and coma. Typical shock syndrome (apnea, circulatory collapse, respiratory arrest, and death) may occur.

Gardenal Patient Information

PATIENT INFORMATION

Practitioners should give the following information and instructions to patients receiving barbiturates:

1. The use of phenobarbital carries with it an associated risk of psychological and/or physical dependence.
The patient should be warned against increasing the dose of the drug without consulting a physician.

2. Phenobarbital may impair mental and/or physical abilities required for the performance of potentially
hazardous tasks (e.g., driving, operating machinery, etc.).

3. Alcohol should not be consumed while taking phenobarbital. Concurrent use of phenobarbital with other
CNS depressants (e.g., alcohol, narcotics, tranquilizers, and antihistamines) may result in additional CNS
depressant

Gardenal Organisms Affected

Humans and other mammals