Galanthamine base en es it fr

Galanthamine base Brand names, Galanthamine base Analogs

Galanthamine base Brand Names Mixture

  • No information avaliable

Galanthamine base Chemical_Formula


Galanthamine base RX_link

Galanthamine base fda sheet

Galanthamine_base FDA

Galanthamine base msds (material safety sheet)

Galanthamine_base MSDS

Galanthamine base Synthesis Reference

Czollner, L. et al. ARKIVOC 191-200 (2001).

Galanthamine base Molecular Weight

287.354 g/mol

Galanthamine base Melting Point

269-270 oC (HBr salt)

Galanthamine base H2O Solubility

10 mg/mL (HBr salt)

Galanthamine base State


Galanthamine base LogP


Galanthamine base Dosage Forms

Capsules (extended-release)

Galanthamine base Indication

For the treatment of mild to moderate dementia of the Alzheimer's type.

Galanthamine base Pharmacology

Galantamine is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor. Galantamine is indicated for the treatment of mild to moderate dementia of the Alzheimer's type. Galantamine is postulated to exert its therapeutic effect by enhancing cholinergic function. This is accomplished by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase. If this proposed mechanism of action is correct, Galantamine's effect may lessen as the disease process advances and fewer cholinergic neurons remain functionally intact. There is no evidence that Galantamine alters the course of the underlying dementing process.

Galanthamine base Absorption

No information avaliable

Galanthamine base side effects and Toxicity

LD50=75 mg/kg (rat)

Galanthamine base Patient Information

Galantamine is used to treat the symptoms of Alzheimer's disease (AD; a brain disease that slowly destroys the memory and the ability to think, learn, communicate and handle daily activities). Galantamine is in a class of medications called acetylcholinesterase inhibitors. It works by increasing the amount of a certain natural substance in the brain that is needed for memory and thought. Galantamine may improve the ability to think and remember or slow the loss of these abilities in people who have AD. However, galantamine will not cure AD or prevent the loss of mental abilities at some time in the future.

Galanthamine base Organisms Affected

Humans and other mammals