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GH Brand names, GH Analogs

GH Brand Names Mixture

  • No information avaliable

GH Chemical_Formula

C990H1532N262O300S7

GH RX_link

http://www.rxlist.com/cgi/generic3/somavert.htm

GH fda sheet

GH msds (material safety sheet)

GH Synthesis Reference

No information avaliable

GH Molecular Weight

22129.0

GH Melting Point

76 oC at pH 3.5 (Gomez-Orellana, I. et al., Protein Sci. 7:1352-1358 (1998).

GH H2O Solubility

No information avaliable

GH State

Liquid

GH LogP

-0.411

GH Dosage Forms

Solution (Subcutaneous Injection); Powder

GH Indication

For treatment of acromegaly

GH Pharmacology

Somavert is used for the treatment of acromegaly, which arises from excessive IGF-1 levels. Somavert selectively binds to growth hormone (GH) receptors on cell surfaces, where it blocks the binding of endogenous GH, and thus interferes with GH signal transduction. Inhibition of GH action results in decreased serum concentrations of insulin-like growth factor-I (IGF-I), and IGF binding protein-3 (IGFBP-3). This reduces the symptoms of acromegaly.

GH Absorption

No information avaliable

GH side effects and Toxicity

No information avaliable

GH Patient Information

BIOD00044.html

GH Organisms Affected

Humans and other mammals