Frenolyse
Frenolyse Brand names, Frenolyse Analogs
Frenolyse Brand Names Mixture
- No information avaliable
Frenolyse Chemical_Formula
C21H28N2O5
Frenolyse RX_link
http://www.rxlist.com/cgi/generic3/trimethbenz.htm
Frenolyse fda sheet
Frenolyse msds (material safety sheet)
Frenolyse Synthesis Reference
No information avaliable
Frenolyse Molecular Weight
388.458 g/mol
Frenolyse Melting Point
188.7 oC
Frenolyse H2O Solubility
40 mg/L
Frenolyse State
Solid
Frenolyse LogP
2.784
Frenolyse Dosage Forms
Capsules (300 mg) for oral administration; Suppositories (200 mg); Injectable (100 mg, 200 mg)
Frenolyse Indication
For the treatment of postoperative nausea and vomiting and for nausea associated with gastroenteritis.
Frenolyse Pharmacology
Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric copper sulfate.
Frenolyse Absorption
The relative bioavailability of the capsule formulation compared to the solution is 100%.
Frenolyse side effects and Toxicity
Oral LD50 in mice is 1600 mg/kg.
Frenolyse Patient Information
No information avaliable
Frenolyse Organisms Affected
Humans and other mammals
