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Fomepizole Brand names, Fomepizole Analogs

Fomepizole Brand Names Mixture

  • No information avaliable

Fomepizole Chemical_Formula


Fomepizole RX_link

Fomepizole fda sheet

Fomepizole msds (material safety sheet)

Fomepizole MSDS

Fomepizole Synthesis Reference

No information avaliable

Fomepizole Molecular Weight

82.1039 g/mol

Fomepizole Melting Point

25 oC

Fomepizole H2O Solubility

No information avaliable

Fomepizole State


Fomepizole LogP


Fomepizole Dosage Forms


Fomepizole Indication

Antizol is indicated as an antidote for ethylene glycol (such as antifreeze) or methanol poisoning, or for use in suspected ethylene glycol or methanol ingestion, either alone or in combination with hemodialysis

Fomepizole Pharmacology

Fomepizole is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites. Ethylene glycol is first metabolized to glycoaldehyde which then undergoes further oxidation to glycolate, glyoxylate, and oxalate. It is glycolate and oxalate that are primarily responsible for the metabolic acidosis and renal damage that are seen in ethylene glycol poisoning. {01}{03} Methanol is first metabolized to formaldehyde and then undergoes subsequent oxidation via formaldehyde dehydrogenase to become formic acid. It is formic acid that is primarily responsible for the metabolic acidosis and visual disturbances that are associated with methanol poisoning.

Fomepizole Absorption

Rapid and complete

Fomepizole side effects and Toxicity

Headache, nausea, dizziness

Fomepizole Patient Information

Fomepizole Organisms Affected

Humans and other mammals