Foille_Insetti

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Foille_Insetti




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Foille_Insetti Brand names, Foille_Insetti Analogs

Foille_Insetti Brand Names Mixture

  • No information avaliable
  • Foille_Insetti Chemical_Formula

    C21H30O5

    Foille_Insetti RX_link

    http://www.rxlist.com/cgi/generic/hydrocortisone.htm

    Foille_Insetti fda sheet

    Foille_Insetti FDA

    Foille_Insetti msds (material safety sheet)

    Foille_Insetti MSDS

    Foille_Insetti Synthesis Reference

    No information avaliable

    Foille_Insetti Molecular Weight

    362.46 g/mol

    Foille_Insetti Melting Point

    220 oC

    Foille_Insetti H2O Solubility

    320 mg/L

    Foille_Insetti State

    Solid

    Foille_Insetti LogP

    1.692

    Foille_Insetti Dosage Forms

    Cream; Ointment; Enemas

    Foille_Insetti Indication

    For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many immune and allergic disorders, such as arthritis, lupus, severe psoriasis, severe asthma, ulcerative colitis, and Crohn's disease.

    Foille_Insetti Pharmacology

    Hydrocortisone is the most important human glucocorticoid. It is essential for life and regulates or supports a variety of important cardiovascular, metabolic, immunologic and homeostatic functions. Topical hydrocortisone is used for its anti-inflammatory or immunosuppressive properties to treat inflammation due to corticosteroid-responsive dermatoses. Glucocorticoids are a class of steroid hormones characterised by an ability to bind with the cortisol receptor and trigger a variety of important cardiovascular, metabolic, immunologic and homeostatic effects. Glucocorticoids are distinguished from mineralocorticoids and sex steroids by having different receptors, target cells, and effects. Technically, the term corticosteroid refers to both glucocorticoids and mineralocorticoids, but is often used as a synonym for glucocorticoid. Glucocorticoids suppress cell-mediated immunity. They act by inhibiting genes that code for the cytokines IL-1, IL-2, IL-3, IL-4, IL-5, IL-6, IL-8 and TNF-alpha, the most important of which is the IL-2. Reduced cytokine production limits T cell proliferation. Glucocorticoids also suppress humoral immunity, causing B cells to express lower amounts of IL-2 and IL-2 receptors. This diminishes both B cell clonal expansion and antibody synthesis. The diminished amounts of IL-2 also leads to fewer T lymphocyte cells being activated.

    Foille_Insetti Absorption

    Topical corticosteroids can be absorbed from normal intact skin. Inflammation and/or other disease processes in the skin increase percutaneous absorption.

    Foille_Insetti Toxicity

    Side effects include inhibition of bone formation, suppression of calcium absorption and delayed wound healing

    Foille_Insetti Patient Information

    No information avaliable

    Foille_Insetti Organisms Affected

    Humans and other mammals